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At Hysigen Bioscience, we are committed to empowering researchers worldwide with premium gene-editing services and innovative products. Leveraging advanced research and development platforms alongside our expert team, we partner with scientists to elevate clinical research, deepen gene function studies, and advance diagnostics. At Hysigen, we ensure that every solution we develop provides a robust foundation for your groundbreaking work.

Gene Editing Services
Lentivirus & AAV packaging
Large Fragment Knockout, 1-50 Kb Protein Knockout guarantee
Large Fragment Knockin, 1-5 Kb 100% Knockin guarantee
Prime Editor / RNP / Base Editing 100% mutation guarantee
HyCyte Cell Products
More than 400 types of Cell lines in stock
STR report
KO cell Lines MU cell Lines KI cell Lines
40+ plasmid Libraries 40+ viral Libraries 400+ cell Pool Libraries
eGFP/Luc Lentivirus hTERT/SV40T Lentivirus Cas9  Lentivirus
Publications


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IF: 52.7

Xu Y, Zheng Y, Liu Y, Wei C, Ren J, Zuo W, Gu R, Liu H, Deng X, Liu Y, Shang X, Ge W, Li Z, Huang Y, He D, Shen X, Wang Z, Lyu C, Wang Z, Mu Y, Zhang Z, Wu H, Li H, Cao B. Ninjurin-1 mediates cell lysis and detrimental inflammation of PANoptosis during influenza A virus infection. Signal Transduct Target Ther. 2025 Sep 23;10(1):307. doi: 10.1038/s41392-025-02391-9.

IF: 45.5

Chen Y, Chen S, Liu Z, Wang Y, An N,

Chen Y, Peng Y, Liu Z, Liu Q, Hu X.

Red blood cells undergo lytic

programmed cell death involving

NLRP3. Cell. 2025 Apr 16:S0092-8674(25)00389-7.


IF: 39.3

Ma B, Ju A, Zhang S, et al.

Albumosomes formed by

cytoplasmic pre-folding

albumin maintain mitochondrial

homeostasis and inhibit nonalcoholic

fatty liver disease[J]. Signal

Transduction and Targeted Therapy,

2023, 8(1): 229.

IF: 26.6

Wu W, Pu Y, Gao S, et al. Bacterial

Metabolism-Initiated Nanocatalytic

Tumor Immunotherapy[J].

Nano-Micro Letters, 2022, 14(1):

1-21.

IF: 37.3

Zheng Z, Zeng X, Zhu Y, et al.

CircPPAP2B controls metastasis of

clear cell renal cell carcinoma via

HNRNPC-dependent alternative

splicing and targeting the miR-182-

5p/CYP1B1 axis[J]. Molecular Cancer,

2024, 23(1): 4.

IF: 18.9

Sun J, Yang F, Wang L, et al. Delivery

of coenzyme Q10 loaded micelle

targets mitochondrial ROS and

enhances efficiency of mesenchymal

stem cell therapy in intervertebral

disc degeneration[J]. Bioactive

Materials, 2023, 23: 247-260.

IF: 18.9

Wei X, Wang L, Duan C, et al. Cardiac

patches made of brown adipose-derived

stem cell sheets and conductive

electrospun nanofibers restore infarcted

heart for ischemic myocardial infarction[J]. Bioactive Materials, 2023, 27: 271-287.

IF: 16

Gao Y, Zhu Y, Wang H, et al.

Lipid-mediated phase separation of

AGO proteins on the ER controls

nascent-peptide ubiquitination[J].

Molecular Cell, 2022, 82(7):

1313-1328. e8.

IF: 15.1

Chen X, Hao Y, Liu Y, et al.

NAT10/ac4C/FOXP1 promotes

malignant progression and

facilitates immunosuppression by

reprogramming glycolytic

metabolism in cervical cancer[J].

Advanced Science, 2023, 10(32):

2302705.

IF: 12.8

Yang H H, Jiang H L, Tao J H, et al.

Mitochondrial citrate accumulation

drives alveolar epithelial cell

necroptosis in lipopolysaccharide

-induced acute lung injury[J].

Experimental & Molecular Medicine,

2022, 54(11): 2077-2091.

Are you ready to take your studies to the next level?
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Address: 56 Sugar Creek Blvd Suite 375, Sugar Land, TX 77478

Email: info@hysigen.com

Telephone: 628-777-8169 (US)

Accelerate research, empower industry